Humboldt, Kansas, is the birthplace of Walter P. Johnson, “The Big Train,” baseball pioneer and one of the original five Hall of Fame inductees along with Babe Ruth and Ty Cobb. George Sweatt of the Kansas City Monarchs Baseball Hall of Fame was also a native of Humboldt. He was the first Black athlete to letter at Pittsburg State University.

In the fall of 1856, B. M. Blanton, a Methodist missionary making a trip through southern Kansas, became impressed with the level valley of lands on both the east and west banks of the Neosho River as an ideal town site. After returning to Lawrence,he told his brother, Napoleon Bonaparte Blanton and J.A. Coffey to induce German members of the New England Immigrant Society, organized in Hartford, Connecticut, to leave Lawrence and help them establish a Free State town on the site in 1857. Later, the Humboldt Town Company was organized and the town named in honor of Baron Alexander Von Humboldt, the German philosopher, geographer, and scientist. In 1861, the U.S. Land Office was moved to Humboldt from Ft. Scott, and Humboldt became more prosperous than most of the Kansas towns as visitors flooded in to register their lands. There was also a large trade with the Indian tribes to the south and west. In September of 1861, after Civil War had broken out and the men were gone to fight, the unprotected town was robbed by a band of Missouri guerillas then burned by Confederate troops in Oct.

Humboldt did rebuild and, after the war, progressed rapidly, especially with the arrival of both the M.K.& T. and the L.L.& G. Railroads.